Hepatitis C in the Newborn

Who should be tested for Hepatitis C?

  • Woman know to be IV drug users

  • Women known to be either HepB or HIV +ve

  • Women whose partner is known to be HepC +ve

  • Any woman already known to be Hepatitis C +ve

Management in pregnancy

  • Send blood for HepC antibody screen (clotted sample)

  • If +ve (or already known +ve) send blood for repeat HepC antibody (clotted) + Hep C viral load (EDTA tube)

Transmission risk to baby

  • The transmission risk is low – approximately 2% and there is no evidence that Caesarean section or avoidance of breast feeding reduce the risk.

  • The only exception to this is in women with high HepC viral loads or co-existing HIV, in which case specialist advice should be sought.

Precautions

  • Appropriate protection including goggles should be worn at delivery.

  • Gloves to be worn for disposing of any bodily wastes, which should be placed in double yellow bags.

  • All blood tests must have ‘Risk of infection’ stickers attached.

Testing of baby (not cord blood)

  • Send blood for HepC ‘qualitative’ PCR (EDTA tube) on 1 day, paediatric consultant follow-up at 3 months.

  • Further follow-up at 1 year with blood test on the day for ‘qualitative PCR’ (red top) & antibodies.

References

www.hepc.nhs.uk

www.hpa.org.uk

N Hadzic. Hepatitis C in pregnancy. Arch Dis Child Fetal Neonatal Ed 2001; 84: F201-204.

Version Control

Version6
Lead AuthorDr A Yannoulias
ApprovedApproved at Paediatrics CG, 19 June 2024
Next reviewJuly 2027
KeywordsHepatitis C, hepC, antibodies, viral load

Version History

VersionDateAuthor(s)
1April 2003Dr R Jones, Dr M McIntyre
2July 2007
3July 2008
4July 2015Dr A Yannoulias
5August 2018Dr A Yannoulias
6June 2024Dr A Yannoulias